What are thermogenic probiotics? Is Provitalize a thermogenic probiotic? Does Provitalize Thermogenic Probiotic work in against dysbiosis in menopause and improve overall health and wellness? What are the side effects of Provitalize? Here are the Provitalize reviews of scientific studies on Provitalize Ingredients that helped us analyze if Provitalize actually works in weight management, maintaining a healthy gut microbiome, and preventing diseases. We have analyzed each ingredient of Provitalize in-depth including thermogenic probiotic ingredients such as Lactobacillus gasseri (L. Gasseri) SBT2055, Bifidobacterium Breve IDCC4401 (B. Breve) and Bifidobacterium Lactis R101-8 along with herbal extracts including Turmeric root extract, Moringa and Curry leaf extract, and absorption enhancers such as Biperine (piperine extract), sunflower lecithin, and delayed-release capsule DRcaps, to ascertain if Provitalize probiotic is for you.
What are Probiotics?
As per the World Health Organization, Probiotics are live microorganisms that confer health benefits to the host when administered in adequate amounts. Probiotics are known to have a beneficial effect on gut health and human health in general. Commonly, probiotics are found in yogurt or other fermented foods, dietary supplements, etc. These probiotics help in the digestion of food, and also in destroying disease-causing cells, or to produce vitamins (1). They inhibit the growth of pathogens in the GIT and reduce the risk of colon cancer and bowel diseases.
Probiotics are not only helpful in gut health, but recent studies suggest that alterations in gut microbiota could have an effect throughout the body. Hence, probiotics have a widespread impact on the immune, endocrine, cardiovascular, and central nervous systems (2). Further, probiotics are both strain-specific and disease-specific; hence, it becomes important to identify a particular strain that produces a particular outcome in a particular disease. One cannot generalize the same.
Usually, probiotic products contain the same microorganisms that naturally live inside our bodies. The most common type of bacteria identified as probiotic in humans is Lactobacillus, Bifidobacterium, and Enterococcus. Bifidobacterium is most abundantly present in the human gut. Others such as yeasts like Saccharomyces boulardii are also used in Probiotic products.
In this blog, we will provide Provitalize reviews as a probiotic in dysbiosis and weight management in menopause. Let us first understand what dysbiosis is, and the connection between gut microbiome and menopause.
What is Dysbiosis?
The adult human gut contains about 1014 bacterial cells and a diverse range of bacteria of about 1000 different species. The gut microbiome harbors both protective and potentially harmful bacteria. The microbiota has a commensal relationship with the host; while the gut provides a suitable environment for the bacteria to survive, the host benefits from its protective functions. In healthy persons, therefore, a balance exists between commensal and pathogenic bacteria in the gut microflora. When this balance is disrupted, a condition known as dysbiosis occurs. Dysbiosis is characterized by an imbalance in bacterial composition, metabolic activities, or distribution (3). Dysbiosis can result in the loss of protective organisms, overgrowth of harmful organisms, and decrease in microbial diversity. These disruptions can contribute to a wide range of diseases like inflammatory bowel disease (IBD), obesity, type 1 diabetes, colorectal cancer, etc.
Gut Microbiome, Dysbiosis and Menopause Connection
Menopause occurs when a woman has ceased menstrual cycle for at least 12 months. The menopausal transition occurs over a span of several years including the perimenopause stage. During this transition, there is a reduction in the number of ovarian follicles leading to decreased estrogen and progesterone hormones. These reductions elevate follicle-stimulating hormone (FSH) during menopausal transition. However, complete depletion of ovarian follicles occurs at menopause leading to very low Estradiol and Progesterone levels. With this background, it has been known that Estradiol and progesterone are also responsible for maintaining the gut barrier. Menopause reduces gut integrity leading to lower gut microbiome diversity and increasing microbial translocation in the gut (4). It has therefore been speculated that gut microbiome could possibly play a role in menopause-associated diseases. Probiotics, due to their potential to modify gut microbiota, could therefore find an important role in the prevention and treatment of menopause-associated conditions.
Further, it is important to note that changes in gut microbiota composition occur not only in the gut but also in the vagina and oral sites, therefore, alterations in gut microbiota have been linked to several diseases in postmenopausal women. The protective role of probiotics altering gut microbiota has been demonstrated in the following conditions linked to menopause (5): Osteoporosis, Breast Cancer, Endometrial hyperplasia, Obesity, Periodontitis, and Cardiometabolic diseases.
Let us see if Provitalize ingredients could help in the above conditions of menopause through its probiotic actions. In the below section, we will review ingredients of Provitalize for the scientific studies and literature to support what it claims. While we provide Provitalize reviews on each of its ingredients to verify the claims made, let us first understand why Provitalize is considered a thermogenic probiotic.
Thermogenic Supplements and Thermogenic Probiotics - What are they?
Thermogenic supplements are those products that increase the metabolic rate and heat production to increase energy expenditure or fat metabolism. These thermogenic supplements are widely used for weight/ fat loss and are known as fat burners. Some examples of thermogenic supplements are Caffeine, Ephedrine, Green tea extract, Capsicum, etc.
Thermogenic probiotics are strains of beneficial bacteria to boost metabolism, reduce cravings, and break down fat cells without causing adverse effects associated with thermogenic supplements like caffeine or ephedrine. Examples of natural thermogenic probiotic strains are Lactobacillus gasseri, B. Breve, B. Lactis, etc. These are found in specific types of yogurt, cottage cheese, or type of milk.
Some of the thermogenic probiotic strains are:
Lactobacillus Gasseri
This probiotic strain supports weight management by reducing abdominal fat and enhancing the body’s natural fat-burning processes.
Lactobacillus Plantarum
This strain is known for its anti-inflammatory properties, thus helping reduce inflammation in the body, and supporting overall health and weight management.
Lactobacillus Acidophilus
This probiotic strain promotes a healthy gut microbiome, aids digestion, and supports immune function.
What is Provitalize? Is it a Thermogenic Probiotic?
Provitalize is a thermogenic probiotic supplement manufactured by Better Body Company (Better body co.) that combines the power of probiotics, natural herbs, and other nutrients to support weight management, hormonal imbalances, and unhealthy gut microbiome for all, particularly after menopause.
Yes, Provitalize is a thermogenic probiotic. As per its official website (6), Provitalize enhances the thermogenic effects of exercise (thereby acting as a thermogenic probiotic) by generating heat in the gut for burning fat.
When we reviewed the literature, we found that the supplement is considered particularly effective in females to boost metabolism and weight management after the 30s or post-menopause.
Provitalize claims to support not only the gut and digestive functions but also manage fat storage, and calorie absorption, reduce cravings, and boost metabolism leading to overall weight management. It is also claimed to improve immunity.
Below are the Provitalize reviews of its ingredients that we found through a thorough literature search.
Provitalize Ingredients Reviews
Provitalize ingredients comprise 3 thermogenic probiotic strains, 3 herbal extracts, and 3 absorption boosters. Let us see and analyze each one of the Provitalize ingredients for reviews of scientific studies on them.
I. Provitalize Reviews of its Thermogenic Probiotic Strains as Ingredients
Provitalize contains the following thermogenic probiotic strains as ingredients and here are the provitalize reviews of scientific studies:
1. Lactobacillus Gasseri (L. Gasseri) SBT2055
Lactobacillus gasseri SBT2055 (LG2055) is a thermogenic probiotic strain of bacteria of human origin that has bile acid tolerance properties and improves the intestinal environment. Several experimental studies have shown that L.gasseri SBT2055 has anti-obesity effects and that it helps in the prevention of abdominal adiposity.
Further, LG2055 has been proven to be safe by clinical studies and does not have any serious side effects.
Moreover, LG2055 has been used for manufacturing dairy products in Japan and is considered to be a safe food ingredient.
Provitalize contains L.gasseri SBT2055 (LG2055) which has proven benefits on the intestinal environment, and obesity and has also been demonstrated to have immune-stimulating and antioxidant effects (7).
Further, there were no serious side effects reported with this Provitalize ingredient.
Other strains of L. gasseri too have weight management properties. For instance, the benefit of daily administration of L. gasseri BNR17 strain for 12 weeks was reported in reducing visceral body fat and waist circumference in obese adults in a randomized clinical trial (8).
2. Bifidobacterium Breve IDCC4401 (B. Breve)
Bifidobacterium Breve IDCC 4401 is present in Provitalize. In addition, B. Breve IDCC4401. While searching for scientific studies on this particular strain, we found cholesterol-lowering activities with the improvement of dyslipidemia.
Provitalize official website mentions that it lowers fat mass, improves γ-glutamyltranspeptidase (GGT), and high-sensitivity C-reactive protein (CRP) in adults with a tendency of obesity. Elevated levels of CRP are observed in inflammation and are a predictor of coronary diseases. GGT is mainly a marker of liver dysfunction. However, we could not find any scientific studies to support the above claims.
Though Bifidobacterium breve has been shown effective for the prevention and treatment of obesity or amelioration of glucose tolerance, and also lowering of CRP, we could not find any studies specifically reported for the IDCC4401 strain. Hence, the manufacturer must validate the claims through scientific literature reviews.
As far as safety is concerned, we found the reports mentioning these Provitalize ingredients to be safe food ingredients without any serious side effects (9).
3. Bifidobacterium Lactis R101-8
II. Provitalize Reviews on its Herbal Ingredients
1. Turmeric Root Extract
Turmeric root extract is obtained from the turmeric plant (Curcuma longa) and is known for its potent health-promoting properties. It has been used for centuries in traditional Ayurvedic and Chinese medicine for its medicinal properties. The major active ingredient responsible for therapeutic actions is curcumin. Turmeric is well-known for its powerful anti-inflammatory potential which has been proven by several scientific studies. Further, it also possesses antioxidant effects that promote overall well-being. Provitalize contains turmeric root extract and hence the claims of antioxidant, anti-inflammatory effects and prevention of heart diseases and other diseases linked to oxidative stress and inflammation.
2. Moringa Leaf Extract
Moringa leaf extract is obtained from the leaves of the Moringa oleifera tree, also called the “Miracle Tree” or “Tree of Life.” Moringa is native to parts of Africa, Asia, and South America and has been used for centuries in traditional medicine. Moringa leaves are full of nutrition and contain essential vitamins, minerals, and antioxidants, including vitamin C, A, calcium, iron, potassium, etc. Quercetin and chlorogenic acid are the antioxidants present in Moringa leaves.
The antioxidant and anti-inflammatory properties of Moringa leaf extract have been explored experimentally in improving learning, memory, and cognitive functions, and also in Alzheimer’s disease with promising effects. The flavonoids and phenolic acids present have also been shown to be neuroprotective. Provitalize has therefore been claimed to support brain health and improve cognitive functions. However, there are limited clinical studies to validate the effects and no Provitalize reviews are available on the subject.
3. Curry Leaf Extract
Curry leaf extract is obtained from the leaves of the curry tree (Murraya koenigii). This is a plant native to India and other parts of Southeast Asia. Curry leaves are widely used in Indian cuisine for their flavor and aroma. Apart from culinary use, they have antioxidant properties, blood sugar-lowering activities, and improved insulin sensitivity. Further, these leaves are known to promote hair growth and protect the skin from free radicals.
Provitalize reviews on the official website claims it fights diabetes and benefits dead hair and the same has been attributed to curry leaf extract.
III. Provitalize Reviews on its Absorption Booster Ingredients
1. Bioperine (Piperine Extract)
Bioperine is a trade name for an extract derived from black pepper (Piper nigrum) that contain high concentrations of the compound piperine. It is commonly used as a bioavailability enhancer in dietary supplements to improve the absorption of various nutrients. Hence it can enhance the absorption of other nutrients such as curcumin, etc. Bioperine is known for its synergistic effects with other nutrients and herbal extracts. When used with curcumin, it can many fold increase its therapeutic effects. Therefore, the provitalize official site mentions it increases the benefits of curcumin by 2000%. So, the bioavailability of curcumin present in the turmeric root extract will be greatly enhanced by Bioperine.
2. Sunflower Lecithin
Sunflower lecithin is a natural substance extracted from sunflower seeds. It is a type of phospholipid that contains various essential fatty acids, including phosphatidylcholine, phosphatidylinositol, and phosphatidylethanolamine. Lecithin is commonly used as an emulsifier and stabilizer in food products and is also available as a dietary supplement. It was mentioned on the official website of Provitalize that sunflower lecithin can increase the effectiveness of the entire Provitalize formula by making all ingredients fat-soluble. As it is an emulsifying agent, it blends and stabilizes oil-based and water-based ingredients. Sunflower lecithin also contains choline which plays a role in brain health. It can be used as an alternative to soy-lecithin if you have a soy allergy.
3. Delayed Release Capsule (DRcaps)
Provitalize Ingredients - Reviews on its Benefits
1. Weight Management
Provitalize’s unique combination of probiotics, natural herbs, and essential nutrients supports a healthy metabolism, aids in fat burning, and helps maintain a healthy weight. The Provitalize ingredients which are particularly responsible for fat-burning effects are the thermogenic probiotic Lactobacillus gasseri SBT2055 (LG2055) and also other ingredients.
2. Gut Health
Provitalize promotes a healthy gut microbiome by replenishing beneficial bacteria through 3 thermogenic probiotic strains thereby improving digestion and reducing inflammation. A healthy gut plays a crucial role in overall health, including weight management in general and for menopause.
3. Brain Health
Provitalize herbal ingredients including Moringa leaf extract and Sunflower lecithin can help promote brain health by improving cognitive functions, learning, and memory, and preventing dementia in individuals. This is also true in menopause.
4. Antioxidant & Anti-inflammatory
The antioxidant and anti-inflammatory actions through thermogenic probiotics, turmeric root extract, and other Provitalize ingredients help in preventing several diseases including heart disease, diabetes, and other inflammatory conditions.
5. Hair and Skin
The curry leaf extract helps promotes hair growth. Further, several Provitalize ingredients have free radical scavenging effects which can help improve skin.
6. Hormonal Balance
The probiotic strains in Provitalize can help regulate hormonal imbalances, particularly in menopausal women, leading to reduced hot flashes, improved mood, and increased overall well-being though there are limited data to support the same.
7. Energy and Vitality
By supporting optimal digestion and nutrient absorption, Provitalize ingredients help increase energy levels and promote a sense of vitality and well-being.
Provitalize Reviews - Does Provitalize Probiotic Work in Menopause?
Provitalize is a dietary supplement that supports overall health and wellness. Though there is limited research or reviews specifically on Provitalize or its ingredients on menopause and we could not find a direct connection between Provitalize and Menopause, a woman may benefit indirectly in several ways post-menopause due to the beneficial properties of its ingredients.
Menopause is associated with significant weight gain. Further, maintaining a healthy gut microbiome is essential during menopause, as hormonal changes can impact digestion and metabolism. Thermogenic Probiotics may help support gut health and maintain a healthy weight.
Menopause is often associated with increased inflammation and oxidative stress. Curcumin present in Turmeric root extract may help reduce inflammation and provide antioxidant support, potentially alleviating symptoms such as joint pain and hot flashes.
Moringa leaf extract, which is rich in antioxidants, vitamins, and minerals, may provide nutritional support during menopause, which is a time when nutrient needs may change. Provitalize contains Moringa leaf extract and its reviews revealed that it has also been studied for its potential benefits on blood sugar control and cholesterol management, which can be important considerations during menopause.
It’s important to note, however, that individual experiences and responses to supplements can vary. Further, we must understand that menopause is a complex physiological process, and it is always advisable to consult with a healthcare professional before starting any new supplement, especially during menopause. They can provide personalized guidance based on your specific health needs and help determine if Provitalize or any other supplement is suitable for you.
Additionally, it’s important to incorporate a comprehensive approach to managing menopause symptoms, including a balanced diet, regular exercise, stress management, and other lifestyle modifications.
Provitalize Side Effects – Is Provitalize Safe?
As we have seen above under the Provitalize ingredients reviews that the supplement contains ingredients that are essentially considered safe. Nevertheless, some individuals may experience side effects with Provitalize or have specific considerations when taking the supplement. The following needs to be kept in mind regarding side effects while taking Provitalize:
1. Allergic Reactions
Some individuals may be allergic to certain ingredients in Provitalize. For example, if you have known allergies to plants in the Asteraceae/Compositae family (such as daisies, ragweed, or marigolds), you must exercise caution as Provitalize contains turmeric root extract, which belongs to this family.
The official website, however, mentions that Provitalize ingredients does not contain gluten, soy, peanuts, dairy, shellfish, or other allergens and therefore these are not considerations for allergic reactions as serious side effects
2. Gastrointestinal Disturbances
Probiotics, including the Lactobacillus gasseri strain in Provitalize, may initially cause mild gastrointestinal symptoms such as bloating, gas, or an upset stomach as side effects. These symptoms are usually temporary and tend to subside as your body adjusts. However, if you experience persistent or severe digestive issues, it is advisable to consult with a healthcare professional.
3. Interactions with other medicines
It’s important to consider potential interactions between Provitalize and any medications you are currently taking for the risk of any adverse interactions resulting in serious side effects. Some ingredients, such as turmeric, may interact with certain medications, including blood thinners, antiplatelet drugs, or medications that affect liver function. If you are taking any prescription medications, it’s recommended to consult with your healthcare provider before starting Provitalize to ensure there are no contraindications or drug interactions.
4. Individual Sensitivities
Each person’s body chemistry is unique, and some individuals may be more sensitive to certain ingredients. It’s possible to experience side effects or an adverse reaction to one or more components of Provitalize, even if they are generally considered safe. Pay attention to any changes in your body, such as rashes, itching, or other unusual symptoms, and discontinue use if you experience any severe or persistent adverse effects.
Always remember, dietary supplements are not intended to diagnose, treat, cure, or prevent any disease, and their effectiveness or side effects or interactions may vary from person to person. It’s important to maintain realistic expectations and prioritize a well-rounded approach to overall health, including a balanced diet, regular exercise, stress management, and other lifestyle factors.
Who manufactures Provitalize?
Provitalize is promoted by Better Body Company which gets it manufactured in a GMP-compliant laboratory in Georgia, USA. The Better Body Co. is a company with offices in Las Vegas, United States, and Singapore, and offers a range of health and wellness products, including dietary supplements. It has been recommended to take 2 capsules a day. It is caffeine-free and stimulant-free as mentioned on the official website. You can also buy it from Amazon.
The Final Words
The Provitalize reviews of its scientific studies on the Provitalize ingredients reveal that it has the potential to support overall health and well-being, potentially providing benefits such as weight management, gut health support, and inflammation reduction. This can also be beneficial during menopause. Further, the Provitalize ingredients are generally considered safe without any serious side effects though individual sensitivities can be different. While individual responses may vary, consulting with a healthcare professional before starting any new supplement is always recommended.
Needless to say, a balanced and diverse gut microbiome is essential for proper digestion, nutrient absorption, immune function, and even brain health. Disturbances in the gut microbiome, such as dysbiosis or a decrease in beneficial bacteria, have been linked to various diseases, including gastrointestinal disorders, autoimmune diseases, obesity, etc. Nurturing a healthy gut microbiome through avoiding excessive antibiotic use, and stress, and having a balanced diet rich in fiber, fermented foods, and probiotic like Provitalize, can help promote overall health and well-being.
Sources
- https://www.nccih.nih.gov/health/probiotics-what-you-need-to-know
- https://pubmed.ncbi.nlm.nih.gov/34492236/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838534/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9379122/
- https://pubmed.ncbi.nlm.nih.gov/36746877/
- https://betterbody.co/pages/pp-provitalize-y?
- https://www.frontiersin.org/articles/10.3389/fnut.2022.1063584/full
- https://www.liebertpub.com/doi/10.1089/jmf.2017.3937
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9706084
- https://pubmed.ncbi.nlm.nih.gov/33135616/
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