Metformin weight loss reviews, how it works and various considerations for taking metformin for weight loss.
Obesity is a growing concern in today’s society, with more than a billion people suffering from this condition worldwide. This prevalence has made it one of the leading causes of various health issues, including heart disease, diabetes, and stroke. As per the World Health Organisation, about 39% of the world’s adult population is obese with a BMI of ≥ 30 kg/m2 (1). In view of above, there has been an increased demand for medical interventions to treat and manage obesity.
While most discussions surrounding this industry highlight more well-known weight loss medications such as the GLP-1 receptor agonists, semaglutide, and liraglutide, metformin has also been a topic of interest in the medical and scientific communities. This is due to its potential to help individuals reach their weight loss goals while also addressing other health conditions.
What is metformin, and how does it work for weight loss?
Metformin is a popular medication used to treat type 2 diabetes and one of the most prescribed medication. It is a prescription medication that belongs to the class of drugs called biguanides. This biguanide boasts a dual action: it helps regulate blood glucose while also assisting with weight management. For those battling both diabetes and obesity, metformin provides a two-pronged approach.
But how does metformin work for weight loss? There is evidence that metformin functions to decrease hepatic glucose production in the liver and reduces absorption of glucose by the intestines. Simultaneously, it may curb appetite and promote feelings of fullness.
A considerable number of studies have demonstrated metformin’s ability to aid weight loss over extended periods. The compound quells hyperglycemia through a multifactorial mode of action, lessening the strain that excessive weight places on metabolic function. Though primarily a sugar-lowering prescription, regular use of metformin confers an added benefit through modest reductions on the scale.
By curbing the desire to overeat, taking metformin for weight loss can support a person’s weight loss efforts by helping them to consume fewer calories and lose excess pounds. Furthermore, metformin has been found to have a positive influence on the gut microbiota. Research has indicated that metformin can alter the composition of the gut bacteria, leading to an improved metabolic function and contributing to a reduction in body weight.
How is metformin accessed and administered?
In the United States, obtaining metformin requires a prescription from a doctor due to its intended use as a treatment for type 2 diabetes. However, some individuals seek out this medication in hopes that it may aid in weight loss efforts. Consultation with a healthcare provider is necessary to ascertain if off-label use of metformin is a suitable option considering one’s complete medical history and current health status. A physician may choose to prescribe metformin off-label for overweight individuals if safely accommodating their condition. Whether approval is granted depends on various risk factors and how well effects can be monitored under a treatment plan tailored to the patient’s specific requirements and circumstances.
When it comes to administration, metformin is typically taken with meals to help prevent a stomach upset, and the dosage may need to be adjusted over time to achieve the desired effect. It is important to follow the doctor’s instructions for taking metformin, as taking too much or too little of the medication can be dangerous.
Metformin Weight Loss Reviews – Considerations for taking metformin for weight loss
Metformin has side effects like other drugs
Common side effects of metformin can include gastrointestinal symptoms such as diarrhea, nausea, and abdominal pain. In some cases, metformin may also cause vitamin B12 deficiency or lactic acidosis, a rare but serious condition that can occur when the body produces too much lactic acid. Individuals should be aware of these potential side effects and discuss any concerns with their healthcare provider before starting metformin for weight loss. This also underscores the importance of only taking this medical under a doctor’s supervision.
Metformin is not a substitute for healthy habits
In the end, we must recognise that metformin is not a substitute for healthy habits. Though there is evidence of this drug offering some assistance in weight management, it should be used in conjunction with lifestyle modifications such as consuming a balanced and nutritious diet and engaging in regular physical activity. Relying solely on metformin without making these lifestyle changes is unlikely to produce significant and sustainable weight loss results.
There is not enough evidence
Though we found a large number of preclinical experiments on metformin, we could not find many clinical trials substantiating the findings. Therefore, systematic human studies must be conducted to know the exact role of metformin for obese individuals.
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